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Filtered Search Results
eMolecules 79218-15-8 | TERT-BUTYL CROTONATE | AstaTech | MFCD00059055 | 142.198 | C8H14O2 | 95.000 | C\C=C\C(=O)OC(C)(C)C | 1g | 718082882
TERT-BUTYL CROTONATE | AstaTech | 79218-15-8 | MFCD00059055 | 142.198 | C8H14O2 | 95.000 | C\C=C\C(=O)OC(C)(C)C | 1g | 718082882
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Medchemexpress LLC ODN 2216 | 332437-00-0 | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G) | 1 MG
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ODN 2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. It induces high amounts of IFN-α and IFN-β, and IFN-α by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). It stimulates IFN-γ production in peripheral blood mononuclear cells (PBMC), indirectly mediated by IFN-α/β.
- Activates NK cells and promotes IFN-γ production of TCR-triggered CD4+ T cells.
- Drives Th1 development of naive CD4 T cells.
- Significantly decreases apoptosis of thymic DC.
- Induces T-cell mediated antitumor immune response in murine vaccination models.
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Medchemexpress LLC Dibutyl maleate | 105-76-0 | 99.2% | 228.28 | 50 G
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Dibutyl maleate, the diester of Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. It can enhance contact sensitization to Fluorescein isothiocyanate in mice.
- Can be used as an intermediate of pharmaceutical synthesis.
- Enhances contact sensitization to Fluorescein isothiocyanate in mice.
- For research use only.
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mM (in 1mL DMSO)
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( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100.0% | 1 ML
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Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood-brain barrier (BBB) and exhibits anti-tumor activity. Perhexiline maleate is used in the research of cancers and cardiovascular diseases like angina.
- Orally active CPT1 and CPT2 inhibitor
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier (BBB)
- Shows anti-tumor activity
- Useful in research for cancers and cardiovascular diseases like angina
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g/mol | C18H24N2O4 | 25 MG
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Cipralisant maleate is a potent, selective histamine H3 receptor ligand used in neuroscience research. It functions as a full antagonist in vivo and shows agonist activity in vitro, with high receptor affinity; it is provided as a solid research chemical for pharmacological and behavioral studies involving wakefulness and attention mechanisms.
- High affinity for histamine H3 receptor.
- Potent antagonist activity in vivo.
- Agonist activity observed in vitro.
- High purity suitable for research applications.
- Available in small-scale quantities with storage recommendations for stability.
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eMolecules 96426-60-7 | Methyl 4-fluorocinnamate | Oakwood Chemical | MFCD00297011 | 180.178 | C10H9FO2 | 99.000 | COC(=O)\C=C\c1ccc(F)cc1 | 25g | 537706891
Methyl 4-fluorocinnamate | Oakwood Chemical | 96426-60-7 | MFCD00297011 | 180.178 | C10H9FO2 | 99.000 | COC(=O)\C=C\c1ccc(F)cc1 | 25g | 537706891
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eMolecules 1785665-61-3 | Medchem Express | VUF11207 (fumarate) | 5mg | 515743918 | HY-110318 | MFCD27991278 | 586.657 | C31H39FN2O8
ChemScene | Methyl 4-amino-35-dichloro-2-fluorobenzoate | 100mg | 746310752 | CS-0612352 | 2649788-83-8 | 238.040 | C8H6Cl2FNO2
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![Medchemexpress LLC Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenylethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) | 599179-03-0 | 99.9% | 649.70 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384336-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenylethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) | 599179-03-0 | 99.9% | 649.70 | 25 MG
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Vicriviroc maleate is a potent, selective, oral bioavailable, and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in PBMC cells. This product is for research use only and not sold to patients.
- Potent and selective CCR5 antagonist
- Oral bioavailable and CNS penetrating
- Inhibits HIV-1 in PBMC cells
- Available as a white to light yellow solid
- Ships at room temperature in continental US
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Medchemexpress LLC Asenapine maleate | 85650-56-2 | 99.95% | 401.84 | 10 MG
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Asenapine maleate, also known by its synonym Org 5222 maleate, is a brain-penetrant atypical antipsychotic. It acts as an antagonist for various receptors, including serotonin, adrenoceptors, dopamine, and histamine receptors. It is investigated for its potential in treating schizophrenia and bipolar disorder.
- Acts as an antagonist of serotonin receptors.
- Exhibits antagonism towards adrenoceptors.
- Functions as a dopamine receptor antagonist.
- Blocks histamine receptors.
- Investigated for its use in schizophrenia.
- Studied for application in bipolar disorder.
- May offer superior therapeutic effects on anxiety symptoms.
- Demonstrates anxiolytic-like effects in behavioral tests in mice.
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Electron Microscopy Sciences N-Butyl Methacrylate 225 ML
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CH₂C(CH₃)CO₂CH₂CH₂CH₂CH₃ F.W. 142.20
Boiling point: 162-164°C
Stabilized with 10ppm MEHQ (Hydroquinone, Mononethylether).
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Medchemexpress LLC Dimethyl fumarate-d6 | 66487-95-4 | MFCD29045610 | >95.0% | 150.16 g/mol | C6H2D6O4 | 10 MG
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Dimethyl fumarate-d6 is a deuterium-labeled analogue of dimethyl fumarate used as a research reagent and analytical standard. It functions as an Nrf2 pathway activator and is employed in studies of antioxidant gene regulation and related signaling. The compound is provided as a solid, with molecular weight 150.16 g/mol and CAS 66487-95-4.
- Deuterium-labeled (d6) analogue for tracer and quantitation studies.
- Activates Nrf2 pathway; useful for oxidative stress research.
- Isotopic purity >95% by NMR; ensures labeling integrity.
- Chemical purity >95.0% (HPLC), suitable for analytical use.
- Molecular weight 150.16 g/mol; formula C6H2D6O4.
- Supplied as a solid, typically used in milligram quantities for assays.
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Medchemexpress LLC AZD9496 | 1639042-08-2 | 10 MG
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AZD9496 is an orally active, selective estrogen receptor degrader (SERD) and an effective, selective estrogen receptor (ERα) antagonist. It demonstrates high potency with an IC50 of 0.28 nM for ERα antagonism and significantly inhibits MCF-7 cell growth.
- Orally active, selective estrogen receptor degrader (SERD)
- Effective and selective estrogen receptor (ERα) antagonist
- IC50 of 0.28 nM for ERα antagonism
- Inhibits MCF-7 cell growth with an EC50 of 0.04 nM
- High selectivity over other nuclear hormone receptors
- Shows significant tumor growth inhibition in estrogen-dependent MCF-7 xenograft models
- Leads to further growth-inhibitory effects when combined with PI3K pathway and CDK4/6 inhibitors
- Demonstrates significant activity in long-term estrogen-deprived models
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eMolecules 130848-06-5 | Medchem Express | Decursinol angelate | 5mg | 624169652 | HY-N4322 | 328.364 | C19H20O5
ChemScene | 3-Chloro-5-(methoxycarbonyl)benzoic acid | 100mg | 694122925 | CS-0320896 | 153203-57-7 | MFCD08458982 | 214.600 | C9H7ClO4
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TARGETMOL CHEMICALS INC PERHEXILINE MALEATE 10MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Also available in 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 uM respectively. purity: 99%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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